TRAZODONE 100 mg
You should not use trazodone if you are allergic to it, or if you are being treated with methylene blue injection.
Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, tranylcypromine and others.
Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using trazodone. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Do not give this medicine to anyone younger than 18 years old without the advice of a doctor. Trazodone is not approved for use in children.
Trazodone is an antidepressant that belongs to a group of drugs called serotonin receptor antagonists and reuptake inhibitors (SARIs). While trazodone is not a true member of the selective serotonin reuptake inhibitors (SSRIs) class of antidepressants, it does still share many properties of the SSRIs.
Trazodone is used to treat major depressive disorder.
Before taking this medicine
You should not use trazodone if you are allergic to it.
Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.
After you stop taking trazodone, you must wait at least 14 days before you start taking an MAOI.
Tell your doctor if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with trazodone could cause a serious condition called serotonin syndrome.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
- liver or kidney disease;
- heart disease, or a recent heart attack;
- a bleeding or blood clotting disorder;
- seizures or epilepsy;
- narrow-angle glaucoma;
- long QT syndrome;
- drug addiction or suicidal thoughts; or
- bipolar disorder (manic depression).
Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Taking trazodone during pregnancy could harm the baby, but stopping the medicine may not be safe for you. Do not start or stop this medicine without asking your doctor.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of trazodone on the baby.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Trazodone is not approved for use by anyone younger than 18 years old.
How should I take trazodone?
Take trazodone exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
Take trazodone after a meal or a snack.
It may take up to 2 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.
You should not stop using this medicine suddenly, or you could have unpleasant symptoms (such as dizziness, vomiting, agitation, sweating, confusion, numbness, tingling, or electric shock feelings). Ask your doctor how to safely stop using this medicine.
Store at room temperature away from moisture, heat, and light.
Dosing information
Usual Adult Dose for Depression:
Initial dose: 150 mg orally per day in divided doses; this may be increased by 50 mg orally per day every 3 to 4 days
Maximum dose:
-Inpatients: 600 mg/day
-Outpatients: 400 mg/day
Comments:
-Patients should be screened for a personal/family history of bipolar disorder, mania, or hypomania prior to initiating treatment.
-Patients should be monitored for withdrawal symptoms when discontinuing therapy.
-After an adequate response has been reached, dosage may be gradually reduced depending on therapeutic response.
-If drowsiness develops, a major portion of the daily dose may be administered at bedtime or a reduction of dosage may be necessary.
-This drug should be taken shortly after a meal or light snack.
Use: Treatment of major depressive disorder (MDD)
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